June 4, 2025

ZO 3-Step Peel Pre- and Post-Treatment Instructions

Pre-Treatment Instructions:

  • To enhance results, start on a ZO® program based on your skin type 4-6 weeks prior to having your first peel. Pigment Control™ and Pigment Control + Blending™ plus tretinoin may be used in patients with a high risk for pigmentation problems.
  • Discontinue the use of topical retinoids and tretinoin (such as Retinol, Retin-A®, Renova®, Differin®,Tazorac®, and Refissa®) 3-4 days prior to Peel.
  • Discontinue the use of alpha hydroxy acids (glycolic acid, lactic acid, etc.), beta hydroxy acids (salicylic acid), benzoyl peroxide, retinols, and other potentially irritating products 3-4 days prior to Peel.
  • Avoid laser procedures, microdermabrasion, electrolysis, waxing and the use of depilatory creams for 5-7 days prior to Peel.
  • Avoid sun exposure or tanning bed 2 weeks prior to your peel.
  • If you have a history of herpes infection will need to start an anti-viral medication (i.e., acyclovir or valacyclovir) one day prior to this peel and continue for 5 days. Notify the office if you need a prescription.

Immediately After ZO 3-Step Peel®

  • Avoid washing face or treated area for at least 5 hours after the peel. Preferably, wait to wash face until the morning after the peel.

Post-Treatment Instructions:

  • Wash face or treated area with the cleanser from your daily ZO® Skin Health program. Wash face gently for 30-40 seconds. Rinse and pat dry.
  • Apply entire packet of Retinol Crème Complex.
  • Apply a thin layer of Hydrating Crème. Hydrating Crème may be applied 3 times daily or more often if needed.
  • Redness, stinging, itching, mild swelling, flaking, and peeling are all normal signs after the peel and vary based on patient responses.
  • Exfoliation will generally begin 2-3 days after treatment and end by day 5.
  • Avoid rubbing, scratching, peeling, or picking the skin with your fingers while healing.
  • Avoid direct sun exposure for at least 7-10 days following the peel. Sunscreen may be used after the skin has completely healed.
  • Besides the Retinol Crème Complex, do not use alpha hydroxy acids, beta hydroxy acids, benzoyl peroxide, retinoids and other potentially irritating products until the skin is healed.
  • Avoid running water directly on your face while showering.
  • Avoid strenuous exercise and sweating until skin is completely healed.
  • Avoid procedures, such as facials, hair removal, microdermabrasion and lasers until skin is fully healed.
  • After skin is healed, return to your daily ZO® Skin Health program.

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